Ampakines: Selective AMPA Receptor Modulators with Potential Benefits
نویسندگان
چکیده
Ya zış ma Ad re si / Add ress rep rint re qu ests to: Feyza Arıcıoğlu Marmara University, School of Pharmacy Department of Pharmacology and Psychopharmacology Research Unit, Haydarpasa, 34668, Istanbul Turkey Telefon / Phone: +90-216-418-9573 Faks / Fax: +90-216-345-2952 Elektronik posta adresi / E-mail address: [email protected] Ka bul ta ri hi / Da te of ac cep tan ce: 21 Kasım 2012 / November 21, 2012
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R,S-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor up-modulators of the benzamide type ("ampakines") have previously been shown to enhance excitatory synaptic transmission in vivo and in vitro and AMPA receptor currents in excised patches. The present study analyzed the effects of an ampakine (CX614; 2H,3H, 6aH-pyrrolidino[2",1"-3',2']1,3-oxazino[6',5'-5,4]benz o[e]1, ...
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